Sparse clinical evidence hinders male infertility therapy development, report says

Male infertility can be caused by a poor lifestyle, amongst others.

Limited clinical evidence and sparse drug development focused on therapies are the leading reasons why male infertility is hard to treat, according to GlobalData.

Moreover, clinical data from randomised controlled trials (RCTs) is rare due to several factors, with very low patient accrual being one of the most difficult challenges.

“It is especially difficult to recruit for infertility trials because of the time-sensitive nature of conception,” David Beauchamp, pharma analyst at GlobalData, comments.

Beauchamp noted that older couples trying to conceive are often unwilling to wait six or more months for a trial treatment arm to conclude.

Male infertility can be caused by poor lifestyle, genetic factors, and certain drug treatments such as testosterone therapy or chemotherapy.

However, a significant percentage are idiopathic, with no identifiable cause.