South Korean researchers develop PDT catheter for oesophageal cancer

The catheter features a stent directly coated with the photosensitiser Al-PcS4.

A research team at South Korea’s Asan Medical Center has developed a new photodynamic therapy (PDT) catheter that enables localised treatment of oesophagal cancer.

The catheter features a stent directly coated with the photosensitiser Al-PcS4, which has traditionally been administered through the bloodstream.

Moreover, a transparent laser delivery channel was also integrated into the stent to ensure even light distribution.

The stent was designed for immediate removal post-treatment, minimising complication risks such as perforation or bleeding associated with long-term stent placement.

This research was supported by a Consolidator Grant under the Personal Basic Research Project, administered by South Korea’s Ministry of Science and ICT and the National Research Foundation.